Buprenorphine is a semi-synthetic opioid derived from thebaine. In 1978 it was marketed as an analgesic (pain killer) for post-operative and cancer patients.
Later it was reformulated as an effective antidote to opiate withdrawal. When prescribed just as pure buprenorphine (Subutex), the medication can be abused – crushed and injected or snorted.
However, brand names such as Suboxone and ZubSolv, add naloxone (opiate overdose reversal medication) to the formulation to make it abuse resistant and prevent overdoses.
However, naloxone in contraindicated for ...Continue Reading →